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- Aubrey de Grey
- Chairman and Chief Science Officer of The Methuselah Foundation.

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His major research interests are the role and etiology of all forms of cellular and molecular damage in mammalian aging, and the design of interventions to reverse the age-related accumulation of such damage. He has published extensively on these and other areas of gerontology, and is also Editor-in-Chief of the high-impact journal Rejuvenation Research, the only peer-reviewed academic journal focusing on intervention in aging.
He has formulated a wide-ranging plan for the comprehensive and eventually indefinite postponement of age-related physical and mental decline, named SENS (Strategies for Engineered Negligible Senescence). He is the organiser of an ongoing series of conferences and workshops that focus on the key biomedical research relevant to SENS, and he also oversees the Methuselah Foundation's growing sponsorship of SENS research worldwide. His main publications are listed here.
- David Gobel
- Chief Executive Officer of the Methuselah Foundation.

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He founded the original non-profit in 2000, which became the Methuselah Foundation in an effort to reverse or preempt the damage of aging and the unimaginable suffering this continues to inflict. He is voraciously curious, a serial entrepreneur, unrepentant do-gooder and technology visionary, having conceived many breakthrough technologies, then going on to found or co-found private and venture capital backed companies and non-profits purpose built to deliver them. Examples are Knowledge Adventure, one of the earliest and most successful educational multimedia software developers to date, Worlds Inc – inventor of shared virtual worlds over the internet, Starbright Foundation’s Starbright World designed to allow hospital bound children to be able to “go out and play” in a rich virtual world and communicate with friends and family, Methuselah Foundation and most recently the SuperCentenarian Research Foundation – focusing on those few among us who are 110 years and older to research why and how they live so long, and what causes them to die.
- David Chambers
- Chief Operating Officer of The Methuselah Foundation.

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He has a long-held interest in leading edge science and technology. With first and Masters degrees in Natural Sciences and Chemical Engineering from the University of Cambridge, UK, he has accumulated extensive commercial experience working in technology and industrial companies, both established and start-up, in the UK and the west coast of the USA. He holds an MBA from London Business School and an MSc in Intellectual Property Law from the University of London. He is a founder/director of a UK distributed database applications start-up and a director of a Singapore-based Asian small cap equity fund. He has been a volunteer with the Methuselah Foundation since 2005.
- Kevin Perrott
- Executive Director of The Mprize competition and Outreach Coordinator of the Methuselah Foundation.

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He has helped build one of the most successful and enduring recreational vehicle dealerships, Riverside Honda in Alberta, Canada, which has been in business for over 40 years, but has also always had a passion for science and compassion for the suffering of others. With the advent of the internet and completion of the human genome project he knew that it was no longer a question of if science could address the suffering of age-related dysfunction and disease, but when, and resolved to put his efforts to that end. In 2003 he met with Dr. Aubrey de Grey at the IABG10 and offered his help in developing the Methuselah Mouse Prize. Since then, with the help of the many Mprize volunteers, he has seen this revolutionary effort grow into a world-transforming example of cooperation. During this time he completed a Bachelor of Science degree specializing in Biochemistry and has entered the PhD. program at the University of Alberta, studying the relationship of mitochondrial dysfunction and aging.
- Jeff Hall
- Executive Director of SENS.

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He is an experienced Electrical Engineer and a student of biology. A graduate of the University of Michigan, he has headed Muse Technologies Inc. for 14 years. Muse Technologies is a research and development engineering firm that specializes in the development of hardware and software systems used in a variety of research labs and industrial settings. His most recent project is an NIH funded research project with the University of Michigan's Human Genetics department. This project's long-term aims are to develop a real-time lab animal monitoring and management system. In 2004, he contacted Aubrey de Grey who encouraged him to delve further into his biology studies. Jeff has been a volunteer with the Methuselah Foundation since 2005 where he also coordinates the Foundation's graphic artists volunteers.
- Allison Taguchi
- Development Officer of the Methuselah Foundation.

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She has over 12 years of fundraising and business development experience at research institutes, universities, government agencies, think tanks, and non-governmental organizations. Examples include: Rushford Nanotech Laboratory, Department of Defense, Oakland Military Institute, and University of Hawaii Biotech Research Center. She holds a Masters Degree in International Affairs & Business Administration form the University of San Diego.
- Elliott Bergman, PhD.
- Mprize Competitor Coordinator.

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He is a Biochemist from Cornell with 37 years industrial experience directing research mostly for major corporations (Shell, Mobil, Stauffer) in the US and England. His areas of expertise include Life Sciences: Biochemistry, Plant and Microbial Biotechnology, AgBiotech, Biology; and Chemistry: Polymer, Catalysis and Small Molecule Chemistry. He is (co)author of a wide range of chemical and biological papers and is (co)inventor on over 20 US Patents. Since 1992 his consulting company ChemLifeSciences has advised VCs, start-ups and public companies in the fields of AgBiotech, CombiChem, HTS, Chemistry, Biopolymers, BioMaterials and BioProcesses. He became deeply involved in antiaging & age-related diseases medicine in 2002, co-founded the SuperCentenarian Research Foundation in 2004, attended SENS conferences in 2003 and 2005, and has worked with the Methuselah Foundation since 2005. Elliot also coordinates SRF-MF interfaces.
- Michael Rae
- Dr. de Grey’s Research Assistant and popular science writer with a strong focus on health and aging.

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He is the author of five scientific articles and commentaries in peer-reviewed scientific journals. Much of his work with the Foundation has been devoted to elucidating the SENS platform for anti-aging biomedicine for a popular audience. His undergraduate minor was in biology. Between 1999 and early 2005, he worked in R&D in the nutraceutical industry, where he was instrumental in shifting company focus into novel molecules with the potential to impact primary and secondary aging.
He is a long-time member and one-time Board Member of the Calorie Restriction Society, a main contributor to the Society’s “How-to Guide,” and core scientific investigator with the CR Society Cohort Study, which seeks to document the feasibility of calorie restriction in humans and the potential human translatability of the anti-aging effects observed in laboratory organisms.
Volunteers
Below are a few of individuals who have given items more precious than money, their skills and their time to help realize a common vision. There are many more likely to whom we owe a debt who have helped us create the organization we have become with gifts of advice, time and effort, and to these we express our deepest gratitude.
- April Smith
- Charles Dorman
- Dave Fisher
- James Swayze
- Jay Fox
- Jim Gibbons
- John Schloendorn
- Mark Hamalainen
- Mark Patterson
- Michael Yamashita
- Neil Gregory
- Nic Greenway
- Reason - LongevityMeme
- Thor Christensen